Kilix supports different layouts by default and you can create more layouts using layout builder.
To assign a layout for a Kilix template style, open the Template Style > Layout Settings panel > and assign a layout for the template style.

By default, Kilix supports 3 layouts:
Home Style 1 Layout

Home Style 2 Layout

Home Style 3 Layout

For further details of Layout Settings in T4 Framework, please go to Layout Settings Documentation